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KMID : 0882420160910030287
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Korean Journal of Medicine
2016 Volume.91 No. 3 p.287 ~ p.291
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Heart Retransplantation to Treat a Case of Refractory Cardiac Allograft Vasculopathy
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Lee Su-Yeon
Choi Jin-Oh
Kim Yu-Jin
Choi Jae-Shin
Lee Ga-Yeon
Kim Jung-Sun
Jeon Eun-Seok
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Abstract
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Cardiac allograft vasculopathy is one of the most important causes of poor long-term survival after heart transplantation. The condition tends to be diffuse, usually affecting the mid-to-distal portions of the coronary artery. Reperfusion therapy is ineffective. Everolimus, an inhibitor of proliferation signaling, has been reported to prevent development of the condition; however, the efficacy thereof has not yet been fully accepted. The only definitive treatment for cardiac allograft vasculopathy is retransplantation. Herein, we describe the case of a 15-year-old boy who underwent heart retransplantation because of rapidly progressive cardiac allograft vasculopathy.
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KEYWORD
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Cardiac allograft vasculopathy, Heart retransplantation
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